We study a class of conformally invariant operators $P$ and their related conformally invariant curvatures $Q$ on even-dimensional Riemannian manifolds. When the manifold is locally conformally flat(LCF) and compact without boundary, $Q$-curvature is naturally related to the integrand in the classical Gauss-Bonnet-Chern formula, i.e., the Pfaffian curvature (CF. Branson, Branson-Gilkey-Pohjanpelto). For a class of even-dimensional complete LCF manifolds with integrable $Q$-curvature, we establish a Gauss-Bonnet-Chern inequality. These are extensions of the classical results of Cohn-Vossen and Huber in dimension two and those of Chang-Qing-Yang in dimension four. As applications, finiteness theorems for certain classes of complete LCF manifolds are also proven.