Mathematics Graduate Student Colloquium

MGSC Website: http://math.uci.edu/~mgsc/

Stochastic Modeling of Stem Cells

Jay Yang
Wednesday, March 1, 2017
3:00 pm - 3:50 pm
RH440R

Talk Abstract:

We are interested in determining the most likely control network(s) that govern the regulation of human colon crypt stem cell lineages, where lineages are comprised of stem cells, transit amplifying cells, and differentiated cells. We started with a theoretically known set of 32 smallest control networks compatible with tissue stability. We proposed and implemented an algorithm of tests where we compared the networks' simulated behavior with the measured observations, and we discovered only 3 candidate networks that are most compatible with the measurements.

About the Speaker:

Jay is a 6th year in the math department. He is a value-driven mathematician/statistician with a focus on Data Science and Computational Biology. He is passionate about solving complex problems and integrating knowledge and skills into practical applications.

Refreshments:

Pizza will be served after the talk.