$A_4 \times \mathbb{Z}_2$ is not isomorphic to $S_4$
because $S_4$ has an element of order $4$, for example the $4$-cycle
$(1\;2\;3\;4)$, whereas $A_4 \times \mathbb{Z}_2$ does not have an element
of order $4$, and having an element of a certain order is a structural property. The elements of $A_4$ have orders $1$, $2$, and $3$ and
the elements of $\mathbb{Z}_2$ have orders $1$ and $2$, so taking least
common multiples we see that the elements of $A_4 \times \mathbb{Z}_2$
have orders $1$, $2$, $3$, and $6$.
Alternatively, one could argue that $A_4 \times \mathbb{Z}_2$ has a
non-identity element that commutes with every element, namely $(\text{identity},
1)$, whereas $S_4$ does not, and the property of having a non-identity
element that commutes with every element is a structural property.