Books

Wodarz, D and Komarova, N.L. (2014) Cancer treatment in silico: small molecule inhibitors and oncolytic viruses. Birkhauser.

Komarova, N.L. and Wodarz, D. (2013) Dynamics of cancer: mathematical foundations of oncology. World Scientific Publishing.

Wodarz, D. and Komarova. N.L. (2005) Computational Biology of Cancer: Lecture notes and mathematical modeling. World Scientific Publishing.

A.V. Korotaev, N.L. Komarova and D.A. Khaltourina (2006) The Laws of History. Century-long cycles and millennial trends. Demography, Economy, Wars. Moscow: URSS (in Russian).

Papers

Pre-prints

186. Kreger, J., Komarova, N. L., & Wodarz, D. (2021). A hybrid stochastic-deterministic approach to explore multiple infection and evolution in HIV.

185. Azizi, A., Komarova, N. L., & Wodarz, D. (2021). Effect of human behavior on the evolution of viral strains during an epidemic.

184. Wang, Y., Boland, C. R., Goel, A., Wodarz, D., & Komarova, N. (2021). The protective effect of aspirin in colorectal carcinogenesis: a multiscale computational study from mutant evolution to age incidence curves.

183. Uhl, P., Lowengrub, J., Komarova, N., & Wodarz, D. (2021). Spatial dynamics of feedback and feedforward regulation in cell lineages.

182. Patel, A. G., Chen, X., Huang, X., Clay, M. R., Komarova, N., Krasin, M. J., ... & Dyer, M. A. (2021). The Myogenesis Program Drives Clonal Selection and Drug Resistance in Rhabdomyosarcoma.

181. Wodarz, D., Komarova, N. L., & Schang, L. M. (2020). Effect of hot zone infection outbreaks on the dynamics of SARS-CoV-2 spread in the community at large.

180. Kreger, J., Brown, D., Komarova, N. L., Wodarz, D., & Pritchard, J. (2021). The role of migration in mutant evolution in fragmented populations.

2021

179. Wodarz, D., Komarova, N. L., & Schang, L. M. (2021). Role of high-dose exposure in transmission hot zones as a driver of SARS-CoV-2 dynamics. Journal of the Royal Society Interface, 18(176), 20200916.

178. Farhang‐Sardroodi, S., Komarova, N. L., Michelen, M., & Pemantle, R. (2021). Success probability for selectively neutral invading species in the line model with a random fitness landscape. Studies in Applied Mathematics, 146(4), 1023-1049.

177. Komarova, N. L., Azizi, A., & Wodarz, D. (2021). Network models and the interpretation of prolonged infection plateaus in the COVID19 pandemic. Epidemics, 35, 100463.

176. Weiss, L. D., van den Driessche, P., Lowengrub, J. S., Wodarz, D., & Komarova, N. L. (2021). Effect of feedback regulation on stem cell fractions in tissues and tumors: Understanding chemoresistance in cancer. Journal of Theoretical Biology, 509, 110499.

175. Kreger, J., Garcia, J., Zhang, H., Komarova, N. L., Wodarz, D., & Levy, D. N. (2021). Quantifying the dynamics of viral recombination during free virus and cell-to-cell transmission in HIV-1 infection. Virus Evolution, 7(1), veab026.

174. Bailey, L. D., & Komarova, N. L. (2021). Cellular feedback networks and their resilience against mutations. Journal of Biological Systems, 29(02), 325-374.

173. Paul, D., & Komarova, N. L. (2021). Multi-scale network targeting: A holistic systems-biology approach to cancer treatment. Progress in Biophysics and Molecular Biology.

2020

172. Komarova, N. L. & Wodarz, D. (2021). Mathematical and Systems Medicine Approaches to Resistance Evolution and Prevention in Cancer. In: Wolkenhauer, Olaf (ed.). Systems Medicine: Integrative, Qualitative and Computational Approaches, vol. 3, pp. 247-260. Oxford: Elsevier.

171. Komarova, N. L., Schang, L. M., & Wodarz, D. (2020). Patterns of the COVID-19 pandemic spread around the world: exponential versus power laws. Journal of the Royal Society Interface, 17(170), 20200518.

170. Komarova, N. L. (2020). Mathematics of Cellular Evolution and Some Biomedical Applications. Notices of the American Mathematical Society, 67(5).

169. Wodarz, D., & Komarova, N. L. (2020). Mutant Evolution in Spatially Structured and Fragmented Expanding Populations. Genetics 216 (1), 191--203.

168. Wodarz, D., Stipp, S., Hirshleifer, D., Komarova, N.L. (2020) Evolutionary Dynamics of Culturally-Transmitted, Fertility-Reducing Traits. Proc Roy Soc B, 287(1925), 20192468.

167. Komarova, N. L., Boland, C. R., Goel, A., & Wodarz, D. (2020). Aspirin and the chemoprevention of cancers: A mathematical and evolutionary dynamics perspective. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, e1487.

166. Kreger, J., Komarova, N.L., Wodarz, D. (2020) Effect of synaptic cell-to-cell transmission and recombination on the evolution of double mutants in HIV. Journal of the Royal Society Interface, 17(164), 20190832.

165. Rodriguez-Brenes, I.A., Wodarz, D., Komarova, N.L. (2020) Beyond the pair approximation: modeling colonization population dynamics. Phys Rev E 101, 032404.

164. Shimura, Tadanobu, Shusuke Toden, Natalia L. Komarova, Richard C. Boland, Dominik Wodarz, and Ajay Goel. (2020) A comprehensive in vivo and mathematical modeling-based kinetic characterization for aspirin-induced chemoprevention in colorectal cancer. Carcinogenesis 41(6), 751-760.

2019

163. Wodarz, D., Levy, D.N. and Komarova, N.L. (2019). Multiple infection of cells changes the dynamics of basic viral evolutionary processes. Evolution letters, 3(1), pp.104-115.

162. Fider, N. and Komarova, N.L. (2019) Differences in color categorization manifested by males and females: a quantitative World Color Survey study. Palgrave Communications 5(1), 1--10.

161. Rockne, Russell C., Andrea Hawkins-Daarud, Kristin R. Swanson, James P. Sluka, James A. Glazier, Paul Macklin, David A. Hormuth II et al. (2019) The 2019 mathematical oncology roadmap. Physical biology 16, no. 4: 041005.

160. Rodriguez-Brenes, I.A., Komarova, N.L., Wodarz, D. (2019) The role of telomere shortening in carcinogenesis: A hybrid stochastic-deterministic approach. Journal of Theoretical Biology 460, 144--152.

159. Farhang-Sardroodi, S., Darooneh, A.H., Kohandel, M. and Komarova, N.L. (2019) Environmental spatial and temporal randomness and its role in non-favored mutant dynamics. Journal of the Royal Society Interface 16(157), 20180781.

158. Ma, T. and Komarova, N.L. (2019) Feature-Label-Order effect when learning from an inconsistent source. Cognitive Science 43(8), e12737.

2018

157. Alvarado, C., Wearing, H.J., Komarova, N.L. (2018) Optimizing homeostatic cell renewal in hierarchical tissues. PLOS Comp. Bio. 14(2), e1005967.

156. Wodarz, D., Newell, A.C., Komarova, N.L. (2018) Passenger mutations can accelerate tumor suppressor gene inactivation in cancer evolution. Journal of The Royal Society Interface, 15(143), 20170967.

155. Ma, T., Wood, K.E., Xu, D., Guidotti, P., Pantano, A., Komarova, N.L. (2018) Admission predictors for success in a mathematics graduate program. Notices of the AMS, vol 65, No 6, p 676.

154. Interiano, M., Kazemi, K., Wang, L., Yang, J., Yu, Z., Komarova, N.L. (2018) Musical trends and predictability of success in contemporary songs in and out of the top charts. Royal Soc Open Science 5, no. 5: 171274.

153. Harris, D., Wodarz, D., Komarova, N.L. (2018) Spatial evolution of regularization in learned behavior of animals. Math Biosci. 299: 103-116.

152. Wood, K.E. & Komarova, N.L. (2018) Cooperation-based branching as a mechanism of evolutionary speciation. Jour. Theor. Bio. 445, 166-186.

151. Fider, N. and Komarova, N.L. (2018) Quantitative study of color category boundaries.JOSA A 35, no. 4 (2018): B165-B183.

150. Alvarado, C., Wearing, H.J., Komarova, N.L. (2018) Optimizing homeostatic cell renewal in hierarchical tissues. PLOS Comp. Bio. 14(2), e1005967.

2017

149. Farhang-Sardroodie, S., Darooneh, A.H., Nikbakht, M., Komarova, N.L., Kohandel, M. (2017) The effect of randomness on the average fixation time of mutants. PLoS Comp. Bio. 13(11), e1005864.

148. Wodarz, D., Goel, A., Komarova, N.L. (2017) Effect of cell cycle duration on somatic evolutionary dynamics. Evolutionary Applications, DOI: 10.1111/eva.12518.

147. Wodarz, D., Goel, A., Boland, C.R., Komarova, N.L. (2017) Effect of aspirin on tumor cell colony formation and evolution. Journal of The Royal Society Interface, 14(134), 20170374.

146. Mahdipour-Shirayeh, A., Darooneh, A. H., Long, A. D., Komarova, N.L., Kohandel, M. (2017) Genotype by random environmental interactions gives an advantage to non-favored minor alleles. Scientific Reports 7: 5193.

145. Yang, J., Axelrod, D., Komarova, N.L. (2017) Determining the control networks regulating stem cell lineages in colonic crypts. Journal of Theoretical Biology 429: 190--203.

144. Fider, N., Narens, L., Jameson, K.A., & Komarova, N.L. (2017) A numerical approach for defining basic color terms and color category best exemplars. JOSA A 34(8): 1285--1300.

143. Zhang, J., Fleischman, A., Wodarz, D. & Komarova, N.L. (2017) Determining the role of inflammation in the selection of JAK2 mutant cells in myeloproliferative neoplasms. Journal of Theoretical Biology 425: 43--52.

142. Komarova, N.L. & van den Driessche, P. (2017) Stability of Control Networks in Autonomous Homeostatic Regulation of Stem Cell Lineages. Bulletin of Mathematical Biology (2017): 1-21.

141. Ma, T. and Komarova, N.L. (2017) Mathematical modeling of learning from an inconsistent source: A nonlinear approach. Bull. Math. Bio. 1--27. DOI: 10.1007/s11538-017-0250-0

140. Zumwalt, T., Wodarz, D., Komarova, N.L., Shusuke, T., Turner, J., Cardenas, J., Burn, J., Chan, A., Boland, C.R., Goel, A. (2017) Aspirin-induced chemoprevention and response kinetics are enhanced by PIK3CA mutations in colorectal cancer cells. Cancer Prevention Research. DOI: 10.1158/1940-6207.CAPR-16-0175

2016

139. Shahriyari, L., Komarova, N.L., Jilkine, A. (2016) The role of cell location and spatial gradients in the evolutionary dynamics of colon and intestinal crypts, Biology Direct 11(1), 42.

138. Law, K. M., Komarova, N. L., Yewdall, A. W., Lee, R. K., Herrera, O. L., Wodarz, D., & Chen, B. K. (2016). In Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection. Cell Reports 15(12), 2771--2783.

137. Sun, Z., Plikus MV, Komarova NL (2016). Near equilibrium calculus of stem cells in application to the airway epithelium lineage. PloS Computational Biology. 12(7), e1004990.

136. Rodriguez-Brenes, I. A., Wodarz, D., & Komarova, N. L. (2016). Cellular replication limits in the Luria-Delbrück mutation model. Physica D: Nonlinear Phenomena, 328, 44-51.

135. Asatryan, A. D., & Komarova, N. L. (2016). Evolution of genetic instability in heterogeneous tumors. Journal of theoretical biology, 396, 1-12.

134. Rische, J. L., & Komarova, N. L. (2016). Regularization of languages by adults and children: A mathematical framework. Cognitive Psychology, 84, 1-30.

2015

133. Komarova, N. L. (2015). The benefits of treating undetectable tumors. eLife, 4, e09713.

132. Yang, J., Plikus, M. V., & Komarova, N. L. (2015). The Role of Symmetric Stem Cell Divisions in Tissue Homeostasis. PLoS Comput Biol, 11(12), e1004629.

131. Rodriguez-Brenes, I. A., Wodarz, D., & Komarova, N. L. (2015). Quantifying replicative senescence as a tumor suppressor pathway and a target for cancer therapy. Scientific reports, 5.

130. Komarova, N.L. (2015) Cancer: a moving target. Nature, 525(7568), 198-199. (News and Views article).

129. Shahriyari, L. and Komarova, N.L. (2015) The role of the bi-compartmental stem cell niche in delaying cancer. Phys. Bio. 12(5): 055001.

128. Yang, J., Sun, Z., and Komarova, N.L. (2015) Analysis of stochastic stem cell models with control. Mathematical Biosciences 266: 93--107.

127. Rodrigues-Brenes, I. A., Wodarz, D. and Komarova, N.L. (2015) Characterizing inhibited tumor growth in stem-cell-driven non-spatial cancers. Mathematical Biosciences doi:10.1016/j.mbs.2015.08.009

126. Asatrian, A., Wodarz, D. and Komarova, N.L. (2015) New virus dynamics in the presence of coinfection. Journal of Theoretical Biology 377:98-109.

125. Toden, S., Okugawa, Y., Jascur, T., Wodarz, D., Komarova, N. L., Buhrmann, C., ...& Goel, A. (2015) Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer. Carcinogenesis, 36(3), 355-367.

124. Kaveh, K, Komarova, N.L., and Kohandel, M. (2015) The duality of spatial death-birth and birth-death processes and limitations of the isothermal theorem. Royal Society Open Science 2: 140465.

123. Foo, J.Y., Haskell, C., Komarova, N.L., Segal, R.A., and Wood, K.E. (2014) Modeling sympatric speciation in quasiperiodic environments. In Applications of Dynamical Systems in Biology and Medicine (pp. 149-174). Springer New York.

2014

122. Wodarz, D., Chan, C., Trinite, B., Komarova, N.L. and Levy, D. (2014) On the laws of virus spread through cell populations. Journal of virology, 88(22), 13240-13248.

121. Komarova, N.L., Burger, J.A., Wodarz, D. (2014) Evolution of ibrutinib resistance in chronic lymphocytic leukemia (CLL). Proceedings of the National Academy of Sciences.

120. Komarova, N. L. (2014). Spatial interactions and cooperation can change the speed of evolution of complex phenotypes. Proceedings of the National Academy of Sciences, 201400828.

119. Mandelshtam, Y. and Komarova, N.L. (2013) When learners surpass their models: mathematical modeling of learning from an inconsistent source. Bulletin of Math Bio.

118. Jackson, T.L., Komarova, N.L. and Swanson, K.R. (2014) Mathematical Oncology: Using Mathematics to Enable Cancer Discoveries. American Mathematical Monthly.

117. Wodarz, D., Garg, N., Komarova, N. L., Benjamini, O., Keating, M. J., Wierda, W. G., Kantarjian, H., James, D., O'Brien, S. & Burger, J. A. (2014). Kinetics of chronic lymphocytic leukemia (CLL) cells in tissues and blood during therapy with the BTK inhibitor ibrutinib. Blood, blood-2014.

116. Manem, V.S.K., M. Kohandel, M., Komarova, N.L., Sivaloganathan, S. (2014) Spatial invasion dynamics on random and unstructured meshes: Implications for heterogeneous tumor populations. Journal of Theor. Biol. 349, 66--73.

115. Wodarz, D., Sorace, R., and Komarova, N.L. (2014)Dynamics of cellular responses to radiation. PLoS Computational Biology , 10(4), e1003513.

114. Komarova, N.L., Shahriyari, L. and Wodarz, D. (2014) Complex role of space in the crossing of fitness valleys by asexual populations. Jour of the Roy Soc Interface, 11(95), 20140014.

113. Rodrigues-Brenes, I. A., Komarova, N.L., Wodarz, D. (2014) Cancer-associated mutations in healthy individuals: assessing the risk of carcinogenesis. Cancer Research, 74(6), 1661-1669.

2013

112. Shahriyari, L. and Komarova, N.L. (2013) Symmetric vs asymmetric stem cell divisions: an adaptation against cancer? PLoS One, 8: e76195.

111. Komarova, N.L. and Boland, C.R. (2013) Cancer: Calculated treatment. Nature 499, 291-292 ( News and Views article).

110. Komarova, N.L. (2013) Principles of regulation of self-renewing cell lineages. PLoS One 8(9), e72847.

109. Wodarz, D. and Komarova, N.L. (2013) Dependence of the firearm-related homicide rate on gun availability: a mathematical analysis. PLoS One 8(7), e71606.

108. Rodrigues-Brenes, I. A., Komarova, N.L., Wodarz, D. (2013) Tumor growth dynamics: insights into somatic evolutionary processes. Trends in Ecology and Evolution, 28: 597-604.

107. Komarova, N.L., Levy, D. and Wodarz, D. (2013) Synaptic transmission and the susceptibility of HIV infection to anti-viral drugs. Scientific Reports 3, 1--8.

106. Rodrigues-Brenes, I. A., Wodarz, D., Komarova, N.L. (2013) Minimizing the risk of cancer: tissue architecture and cellular replication limits. Jour Roy Soc Interface 10(86), 1--12.

105. Wodarz, D, Sun, Z., Lau, J.W., Komarova, N.L. (2013) Nearest neighbor interactions, habitat fragmentation, and the persistence of host-pathogen systems. The American Naturalist, 182(3), E94-E111.

104. Rodrigues-Brenes, I. A., Wodarz, D., Komarova, N.L. (2012) Stem cell control, oscillations and tissue regeneration in spatial and non-spatial models. Front. Oncol. 3:82.

103. Komarova, N.L., Wodarz, D. (2013) Virus dynamics in the presence of synaptic transmission. Math Biosci. 242(2), pp. 161--171.

102. Wodarz, D., Boland, C.R., Goel, A., Komarova, N.L. (2013) Methylation kinetics and CpG-island methylator phenotype status in colorectal cancer cell lines. Biology Direct. 8(1), 1--14.

101. Komarova, N.L. (2013) Spatial stochastic models of cancer: fitness, migration, invasion. Mathematical Biosciences and Engineering 10, pp. 761--775.

100. Komarova, N.L., Jameson, K.A. (2013) Quantitative theory of human color choices. PLoS One 8, e55986.

99. Komarova, N.L., Anghelina, D., Voznesensky, I., Trinite, B., Levy, D., Wodarz, D. (2013) Relative contribution of free virus and synaptic transmission to the spread of HIV through target cell populations. Biology Letters 9(1).

98. Sun, Z., Komarova, N.L. (2013) Stochastic control of proliferation and differentiation in stem cell dynamics. To appear in Jour. Math. Bio.

2012

97. Wodarz, D., Hofacre, A., Lau, J.W., Sun, Z., Fan, H., Komarova, N.L. (2012) Complex spatial dynamics of oncolytic viruses in vitro: mathematical and experimental approaches. PLoS Computational Biology, 8(6): e1002547.

96. Hofacre, A., Wodarz, D, Komarova, N.L., Fan, H. (2012) Early infection and spread of a conditionally replicating adenovirus under conditions of plaque formation. Virology 423(1), 89--96.

95. Thalhauser, C.J., Komarova, N.L. (2012) Alzheimer's disease: rapid and slow progression. Roy. Soc. of London Interface 9(66) 119-126.

94. Komarova, N.L. (2012) The spread of conventions and the search for the optimal strategy (Commentary). Religion, Brain & Behavior, 2, 1--4.

923. Narens, L., Jameson, K.A., Komarova, N.L. and Tauber, S. (2012) Language, Categorization, and convention. Advances in complex systems 15(3), 1150022-1--21.

92. Komarova, N.L. (2012) Axiomatic modeling in life sciences. In R. V. N. Melnik and A. V. Antoniouk, De Gruyter (eds.) Mathematics and Life Sciences , De Gruyter.

91. Komarova, N.L., Urwin, E., Wodarz, D. (2012) Accelerated crossing of fitness valleys through division of labor and cheating. Scientific Reports. 2:917.

90. Sorace, R., Komarova, N.L. (2012) Accumulation of neutral mutations in growing cell colonies with competition. Jour. of Theor. Biol. 314, 84-94.

89. Sun, Z., Komarova, N.L. (2012) Stochastic modeling of stem-cell dynamics with control. Math. Biosciences. 240(2), 231-240.

88. Komarova N.L., Levy D.N., Wodarz D. (2012) Effect of synaptic transmission on viral fitness in HIV infection. To appear in PLoS ONE.

2011

87. Komarova, N.L. (2011) ``Cancer initiation and progression, modeling''. Encyclopedia of Applied and Computational Mathematics. Springer.

86. Thalhauser, C.J., Komarova, N.L. (2011) Calculating stage duration statistics in multistage diseases. PLoS One 6(12): e28298.

85. Komarova, N.L., Thalhauser, C.J. (2011) High degree of heterogeneity in Alzheimer's disease progression patterns. PLoS Comput Biol 7(11): e1002251.

84. Komarova, N.L. (2011) ``Evolutionary rate''. Brenner's Online Encyclopedia of Genetics, edited by Stanley Maloy and Kelly Hughes, 2nd edition.

83. Rodrigues-Brenes, I. A., Komarova, N.L., Wodarz, D. (2011) Evolutionary dynamics of feedback escape and the development of stem-cell driven cancers. PNAS 108(47) 18983-18988.

82. Komarova. N.L.(2011) Mathematical modeling of cyclic treatments of chronic myeloid leukemia Math Biosci and Engineering 8(2): 289--306.

2010

81. Komarova, N.L. (2010) Modeling approaches to studying stem cells in cancer. In S.Sivaloganathan (ed.) New perspectives in mathematical biology (Fields Institute Communications), American Mathematical Society, Providence, Rhode Island.

80. Katouli, A.A., Komarova. N.L. (2010) Optimizing combination therapies with existing and future CML drugs. PLoS One 5(8):e12300.

79. Wan, F.M.Y., Sadovsky, A.V. and Komarova, N.L. (2010) Genetic Instability in Cancer: An Optimal Control Problem. Studies in Applied Mathematics 125 (1): 1 --38.

78. Thalhauser CJ, Komarova NL. (2010) Signal response sensitivity in the yeast mitogen-activated protein kinase cascade. PLoS One.

77. Thalhauser CJ, Lowengrub JS, Stupack D, Komarova NL. (2010) Selection in spatial stochastic models of cancer: migration as a key modulator of fitness. Biol Direct.

76. Katouli AA, Komarova NL. (2010) The Worst Drug Rule Revisited: Mathematical Modeling of Cyclic Cancer Treatments. Bull Math Biol.

75. Komarova NL, Levin SA. (2010) Eavesdropping and language dynamics. J Theor Biol. 264(1):104-18.

74. Komarova NL, Wodarz D.(2010) ODE models for oncolytic virus dynamics. J Theor Biol. 263(4):530-43.

2009

73. Komarova, N.L. (2009) Building mathematical models for drug treatment of cancer. T.S. Deisboeck & G. Stamatakos (eds.) Multiscale Cancer Modeling, Chapman & Hall.

72. Komarova, N.L., Katouli, A.A. & Wodarz, D. (2009) Combination of two but not three current targeted drugs can improve therapy of chronic myeloid leukemia. PLoS One 4(2):e4423.

71. Jaeger, H., A. Baronchelli, E. Briscoe, M. H. Christiansen, T. Griffiths, G. Jaeger, S. Kirby, N. Komarova, P. J. Richerson, L. Steels and J. Triesch. What can mathematical, computational and robotic models tell us about the origins of syntax? In D. Bickerton and E. Szathmary. (eds.), Biological Foundations and Origin of Syntax, Struengmann Forum Reports, vol. 3. Cambridge, MA: MIT Press. 2009.

70. Komarova, N.L. & Wodarz, D. (2009) Towards predictive computational models of oncolytic virus dynamics in vitro. PLoS One (1):e4271.

69. Komarova, N.L. & Wodarz, D. (2009) Combination therapies against chronic myeloid leukemia: short term versus long term strategies. Cancer Res. 69, 4904.

68. Boland, C.R., Komarova, N.L. & Goel, A. (2009) Chromosomal instability and cancer: not just one CINgle mechanism. Gut 58(2):163-4.

67. Thalhauser, C.J and Komarova, N.L. (2008) Specificity and robustness of the mammalian MAPK-IEG network. To appear in Biophys. Journ.

66. Jameson, K.A. & Komarova, N.L. (2009) Evolutionary models of color categorization. I. Population categorization systems based on normal and dichromat observers. Jour. Opt. Soc. Amer. 26, pp. 1414-1423.

65. Jameson, K.A. & Komarova, N.L. (2009) Evolutionary models of color categorization. II. Realistic observer models and population heterogeneity. Jour. Opt. Soc. Amer. 26, pp. 1424-1436 .

2008

64. Komarova, N.L. and Jameson, K.A. (2008) Population heterogeneity and color stimulus heterogeneity in agent-based color categorization. Jour. Theor. Biol. 253(4):680-700.

63. Komarova, N.L., Sadovsky, A.V. and Wan, F.M.Y. (2008) Selective pressures for and against genetic instability in cancer: a time-dependent problem. Jour. of the Royal Society Interface, 5(18): 105-21.

2007

62. Komarova, N.L. and Wodarz, D. (2007) Stochastic modeling of cellular colonies with quiescence: an application to drug resistance in cancer. Theor Popul Bio. 72(4):523-38.

61. Komarova, N.L. and Wodarz, D. (2007) Cancer as a microevolutionary process. To appear in Evolution in health and disease, 2nd edition, Oxford University Press (Ed: Stephen Stearns and Jacob Koella).

60. Komarova, N.L., Wodarz, D., Boland, C.R. & Goel, A. (2007) Genetic and epigenetic pathways to colon cancer: relating experimental evidence with modeling. To appear in Nicola Bellomo, Mark Chaplain, and Elena De Angelis (Eds), Selected topics on cancer modeling: genesis - evolution - immune competition - therapy. Birkhauser, Boston.

59. Komarova, N.L. (2007) Stochastic Modelling of Loss- and Gain-of-Function Mutations in Cancer. To appear in Mathematical Models and Methods in Applied Sciences 17S: 1647-1773.

58. Komarova, N.L. (2007) Loss- and gain-of-function mutations in cancer: mass-action, spatial and hierarchical models. Jour. Stat. Phys. 128, pp. 413-446.

57. Wodarz, D. and Komarova, N.L. (2007) Can loss of apoptosis protect against cancer? Trends in Genetics 23(5), pp. 232-7.

56. Komarova, N.L., Baldi, P. and Wu, L. (2007) The fixed-size Luria-Delbruck model with a nonzero death rate. Math. Biosciences 210(1):253-90.

55. Komarova, N.L., Zou, X., Nie, Q. & Bardwell, L. (2007) Mathematical Models of Specificity in Cell Signaling. Biophys Jour. 92(10), pp. 3425-41

54. Komarova, N.L., Jameson, K.A. and Narens, L. (2007) Evolutionary models of color categorization based on discrimination. Journal of Math Psychology 51(6):359--382.

53. Komarova, N.L. and Wodarz, D. (2007) Effect of cellular quiescence on the success of targeted CML therapy. PloS ONE, 2(10):e990.

52. Komarova NL. (2007) Viral reproductive strategies: How can lytic viruses be evolutionarily competitive? Jour Theor Biol. 249(4):766-84.

2006

51. Komarova, N.L. (2006) Spatial stochastic models of cancer initiation and progression. Bull. Math. Biol. DOI: 10.1007/s11538-005-9046-8, pp. 1-27.

50. Komarova, N.L. & Cheng, P. (2006) Epithelial tissue architecture protects against cancer. Math Biosciences , 200(1), pp 90-117.

49. Komarova, N.L. (2006) Language and mathematics: an evolutionary model of grammatical communication. In L. Grinin, V.C. de Munck and A. Korotaev (eds), History and Mathematics: Analysing and modeling global development , URSS, Moscow.

48. Komarova, N.L. (2006) Oscillations in population sizes - from ecology to history (a commentary). Structure and Dynamics: eJournal of Anthropological and Related Sciences , 1(1), Article 8.

47. Komarova, N.L. (2006) Population dynamics of human language: a complex system. Frontiers of engineering: reports on leading-edge engineering from the 2005 symposium, The National Academy Press, pp. 89-98.

46. Komarova, N.L. (2006) Stochastic modeling of drug resistance in cancer. Jour. Theor. Biol. , 239(3), pp. 351-366

2005

45. Komarova, N.L., Zou, X., Nie, Q. & Bardwell, L. (2005) A theoretical framework for specificity in cell signaling. Molecular Systems Biol. doi:10.1038/msb4100031, E1-E5

44. Wodarz, D. and Komarova, N.L. (2005) Evolutionary dynamics of drug resistance in cancer (review). Gene Therapy and Mol. Biol. 9, pp. 247-256.

43. Komarova, N.L. (2005) Cancer, aging and the optimal tissue design. Semin Cancer Biol., 15(6), pp. 494-505.

42. Wodarz, D. & Komarova, N.L. (2005) Emergence and prevention of resistance against small molecule inhibitors. Semin Cancer Biol. 15(6), pp. 506-14.

41. Komarova, N.L. & Wodarz, D. (2005) Drug resistance in cancer: principles of emergence and prevention. Proc. Natl. Acad. Sci. 102 (27), pp. 9714-9.

40. Komarova, N.L. & Soffer, A. (2005) Nonlinear waves in double-stranded DNA. Bull. Math. Biol. 67(4), pp. 701-718, also arXiv:cond-mat/0411621

39. Komarova, N.L. & Mironov, V. (2005) On the role of endothelial progenitor cells in tumor neovascularization. Jour. Theor. Biol. 235 (3), pp. 338-49

38. Komarova, N.L. (2005) Mathematical modeling of tumorigenesis: mission possible. Curr. Oncology 17(1), pp. 39-43.

37. Iwasa, Y., Michor, F., Komarova, N.L. and Nowak, M. (2005) Population genetics of tumor suppressor genes. Jour. Theor. Biol. 233 pp. 15-23.

Korotayev, A.V. and Komarova, N.L. (2005) Historical macrodynamics of China, in Korotayev, A.V., Malkov, A.S. and Khaltourina, D.A. The Laws of History. Mathematical Modeling of Historical Macroprocesses. Demography, Economy, Wars. Moscow: URSS (in Rusian).

Khaltourina, D.A., Korotayev, A.V. and Komarova, N.L. (2005) Demographic growth and civil wars in modern Sub-Saharan Africa: mathematical modeling, in Korotayev, A.V., Malkov, A.S. and Khaltourina, D.A. The Laws of History. Mathematical Modeling of Historical Macroprocesses. Demography, Economy, Wars. Moscow: URSS (in Rusian).

36. Nowak, M.A. and Komarova, N.L. (2005) The evolution of altruism: from game theory to human language, in C. Harper (ed.) Spiritual Information: 100 perspectives, Templeton Foundation Press.

2004

35. Komarova, N.L. & Wang, L. (2004). Initiation of colorectal cancer: where do the two hits hit? Cell Cycle 3(13).

34. Komarova, N.L. (2004) Genomic Instability in Cancer: Biological and Mathematical Approaches. Cell Cycle 3(8) 1081-5.

33. Komarova, N.L. (2004) Does cancer solve an optimization problem? Cell cycle 3(7).

32. Nowak, M.A., Michor, F., Komarova, N.L. & Iwasa, Y. (2004) Dynamics of tumor suppressor gene inactivation. Proc. Natl. Acad. Sci. 101, pp. 10635-10638.

31. Komarova, N.L. (2004) Replicator-mutator equation, universality property and population dynamics of learning. Jour. of Theor. Biol. 230(2), pp. 227-239.

30. Komarova, N.L. & Wodarz, D. (2004) The optimal rate of chromosome loss for cancer initiation and progression. Proc. Natl. Acad. Sci. 101(18), pp. 7017-7021.

29. Komarova, N.L. and Niyogi, P. (2004) Optimizing the mutual intelligibility of linguistic agents in a shared world. Jour. of Artificial Intelligence, 154(1-2), pp. 1-42.

28. Wodarz, D., Iwasa, Y., and Komarova, N.L. (2004) On the emergence of multifocal cancers. Jour. of Carcinogenesis 3(1) 13.

2003

27. Komarova, N.L. & Wodarz, D. (2003) Evolutionary dynamics of mutator phenotypes in cancer: implications for chemotherapy. Cancer Research 63(20), pp. 6635-42.

26. Komarova, N.L., Sengupta, A. & Nowak, M.A. (2003) Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability. Jour. of Theor. Biol. 223(4), pp. 433-450.

25. Komarova, N.L. & Nowak, M.A. (2003) Language dynamics in finite populations. Jour. of Theor. Biol. 221, pp. 445-457.

24. Krakauer, D.C. and Komarova, N.L. (2003) Levels of selection in positive strand virus dynamics. Journ. Evol. Biol. 16(1), p. 64-73.

23. Michor, F., Iwasa, Y., Komarova, N.L. & Nowak, M.A. (2003) Local regulation of homeostasis favors chromosomal instability. Current Biology, 13, pp. 581-584.

22. Wei, X., Decker, J.M., Wang, S., Hui, H., Kappes, J.C., Wu, X., Salazar, J.F., Salazar, M.G., Kilby, J.M., Saag, M.S., Komarova, N.L., Nowak, M.A., Hahn, B.H., Kwong, P.D. & Shaw, G.M. (2003) Antibody Neutralization and Escape by HIV-1. Nature, 422, pp.307-312.

21. Komarova, N.L., Barnes, E., Klenerman, P. & Wodarz, D. (2003) Boosting immunity by anti-viral drug therapy: a simple relationship between timing, efficacy and success. Proc. Natl. Acad. Sci. 100(4), pp.1855-1860.

20. Komarova, N.L. and Rivin, I. (2003) Harmonic mean, random polynomials and stochastic matrices. Advances in Appl. Math. 31(2), pp.501-526 (math.PR/0105236)

19. Komarova, N.L. and Nowak, M.A. (2003) Language, learning and evolution, in S. Kirby & M. Christiansen (eds.) Language Evolution: The States of the Art, pp. 317-337, Oxford University Press.

18. Komarova, N.L., Lengauer, C., Vogelstein, B. & Nowak, M.A. (2003) Dynamics of genetic instability in sporadic and familial colorectal cancer. Cancer Biology and Therapy , 1(6), pp. 685-692.