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Louis Komzsik
Mon Oct 15, 2018
4:00 pm
Engineering topology optimization is a technique to minimize the mass of a structure while maintaining or even increasing its robustness in certain lifecycle applications. The presentation will show the technical foundation based on the finite element method with an embedded gradient based mathematical optimizer. Characteristic...
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Eberhard Voit
Mon Oct 1, 2018
4:00 pm
Most biological experiments result in snapshots that illustrate select aspects of a phenomenon of interest. These snapshots may be very complicated, consisting of thousands of peaks in a mass spectrogram, the expression levels of whole genomes, or an impressive image visualizing the localization of different proteins. Yet, each result is...
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Bao Wang
Mon May 14, 2018
4:00 pm
First, I will present the Laplacian smoothing gradient descent proposed recently by Prof. Stan Osher. We show that when applied to a variety of machine learning models including softmax regression, convolutional neural nets, generative adversarial nets, and deep reinforcement learning, this very simple surrogate of gradient descent can...
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Jay Newby
Thu Apr 26, 2018
10:00 am
The longstanding view in chemistry and biology is that high-affinity, tight-binding interactions are optimal for many essential functions, such as receptor-ligand interactions. Yet, an increasing number of biological systems are emerging that challenge this view, finding instead that low-affinity, rapidly unbinding dynamics can be essential for...
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Rongjie Lai
Mon Apr 16, 2018
4:00 pm
Analyzing and inferring the underlying global intrinsic structures of data from its local information are critical in many fields. In practice, coherent structures of data allow us to model data as low dimensional manifolds, represented as point clouds, in a possible high dimensional space. Different from image and signal processing which handle...
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Amir Moradifam
Mon Apr 9, 2018
4:00 pm
We study the inverse problem of determining both the source of a wave and its speed inside a medium from measurements of the solution of the wave equation on the boundary. This problem arises in photoacoustic and thermoacoustic tomography, and has important applications in medical imaging. We prove that if $c^{-2}$ is harmonic in $\omega \subset \...
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Keith Promislow
Mon Mar 5, 2018
4:00 pm
The self organization of phospholipids into membranes is fundamental to the origin of life, allowing for protection of internal structure while necessitating machinery to open pores. Evolutionary pressure has designed a myriad of controls in the guise of surface proteins that adjust the entropy of the lipid-solvent interactions...
