Modeling Biofilm Dynamics in Aqueous Environment

Speaker: 

Qi Wang

Institution: 

University of South Carolina

Time: 

Monday, November 5, 2012 - 4:00pm to 5:00pm

Location: 

Rowland Hall 306

I will present a systematic approach to develop models for biofilm and solvent mixture. Models at various time and length scales will be introduced.
Quorum sensing, cell adhesion, and other cellular movement due to chemotaxis and haptotaxis will be discussed. Biofilm growth and interaction with the ambient flow
in an infinitely long channel and a finite length flow chamber will be simulated using a 3-D numerical simulation tool developed based on the models. The role of antimicrobial agents
will be investigated as well.

How to search for transition states/saddle points?

Speaker: 

Qiang Du

Institution: 

Penn State University

Time: 

Monday, October 1, 2012 - 4:00pm to 5:00pm

Host: 

Location: 

RH306

Exploring complex energy landscape is a challenging
issue in many applications. Besides locating equilibrium
states, it is often also important to identify the
transition states given by saddle points. In this talk,
we will discuss the mathematics and algorithms, in
particular, the shrinking dimer dynamics, developed to
compute transition states. Some applications will be
considered, including the study of critical nuclei
morphology in solid state transformations, optimal
photonic crystal design and the generalized Thomson problem.

Dissipative Properties of Systems Composed of High-Loss and Lossless Components

Speaker: 

Aaron Welters

Institution: 

MIT

Time: 

Thursday, August 30, 2012 - 2:00pm to 3:00pm

Host: 

Location: 

RH 306

We study dissipative properties of systems composed of two components one of which is highly lossy and the other is lossless. One of the principal result is that the dissipation causes modal dichotomy, i.e., splitting of the eigenmodes into two distinct classes according to their dissipative properties: high-loss and low-loss modes. Interestingly, larger losses in the lossy component make the entire composite less lossy, the dichotomy more pronounced, low-loss modes less lossy, and high-loss modes less accessible to external excitations. We also have carried out an exhaustive analytical study of the system quality factor. This is joint work with Alexander Figotin.

Fast randomized direct solvers for large discretized PDEs

Speaker: 

Jianlin Xia

Institution: 

Purdue University

Time: 

Monday, October 8, 2012 - 4:00pm to 5:00pm

Host: 

Location: 

RH306

In this talk, I will discuss our recent developments on fast randomized
structured direct methods for large sparse discretized PDEs. The methods
use some structures in practical problems as supported by the fast
multipole method (FMM), and utilizes techniques such as advanced sparse
matrix factorization, randomized sampling, and hierarchically low-rank
approximations.

We incorporate randomization into sparse direct solvers for the purposes
of both higher efficiency and better flexibility than some existing
structured solvers. We show that our direct solvers can achieve nearly
O(n) complexity for some discretized PDEs (such as Helmholtz equations)
in 2D, and O(n)~O(n^{4/3}) complexity in 3D (instead of O(n^2)
classically). The solution costs and memory requirements are about O(n)
for both 2D and 3D, which makes the methods very attractive for
preconditioning and for problems with many right-hand sides such as
seismic imaging.

The insensitivity of the solutions to parameters such as frequencies in
some problems is discussed. The stability and accuracy analysis for the
methods is given. We prove that our methods can generally be more stable
than some standard matrix computations.

We also study various important generalizations and applications, such as
O(n) cost methods for sparse selected inversion (finding diagonal or other
entries of a sparse matrix), matrix-free direct solutions, factorization
update for multiple frequencies, etc.

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