Speaker: 

Prof Hal Stern

Institution: 

UCI

Time: 

Monday, May 23, 2005 - 4:00pm

Location: 

MSTB 122

This talk discusses an extention of a Bayesian approach for estimating the ancestry probability, the probability that an inbred line is an ancestor of a given hybrid, to account for genotyping errors. The effect of such errors on ancestry probability estimates is evaluated through simulation. The simulation study shows that if misclassification is ignored, then ancestry probabilities may be slightly overestimated. The sensitivity of ancestry probability calculations to the assumed genotyping error rate is also assessed. Finally we briefly discuss approaches for estimating the error rate from limited data.